3,4,5-Trimethoxybenzaldehyde CAS 86-81-7

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3,4,5-Trimethoxybenzaldehyde CAS 86-81-7

3,4,5-Trimethoxybenzaldehyde CAS 86-81-7 TMBA, stock available with high quality.

CAS 86-81-7 TMBA Basic Parameter

Product Name 3,4,5-Trimethoxybenzaldehyde
Synonyms 3,4,5-methoxybenzaldehyde;3,4,5-TriMethoxybenzaldenyde;Three,four,five-preparationbenzaldehyde; 3,4,5-tiMethoxybenzaldehyde;3,4,5-TrimethoxybenZHldehyde;TrimetazidineImpurity9;OTAVA-BBBB7018801952
CAS NO 86-81-7
Molecular Formula C10H12O4
Molecular Weight 196.2
EINECS 201-701-6
Melting Point 72-74 °C (lit.)
Boiling Point 163-165 °C/10 mmHg (lit.)
Flash Point 163-165°C/10mm
Density 1.2166 (rough estimate)
Storage Keep in dark place, Sealed in dry, Room Temperature
Solubility Soluble in methanol, solubility is 0.1g/mL, clear
Appearance white to creamy powder or flakes

TMBA Picture

cas 86-81-7, 3,4,5-Trimethoxybenzaldehyde, TMBA

What is 3,4,5-Trimethoxybenzaldehyde?

3,4,5-Trimethoxybenzaldehyde is an organic compound and a biochemical. Within this class of compounds, the chemical is categorized as a trisubstituted aromatic aldehyde.


3,4,5-Trimethoxybenzaldehyde can be used as an intermediate in the synthesis of some pharmaceutical drugs including trimethoprim, cintriamide, roletamide, trimethoquinol (aka tretoquinol), and trimazosin as well as some psychedelic phenethylamines.


Industrial scale

For industrial applications the chemical is synthesized from p-cresol using aromatic substitution with bromine followed by nucleophilic substitution with sodium methoxide. Oxidation of the methyl group to an aldehyde can occur via various synthetic methods.

Laboratory scale 

At the laboratory scale the chemical is conveniently synthesized from vanillin or from Eudesmic acid’s Acyl chloride via Rosenmund reduction.

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