3,4,5-Trimethoxybenzaldehyde CAS 86-81-7
3,4,5-Trimethoxybenzaldehyde CAS 86-81-7 TMBA, stock available with high quality.
CAS 86-81-7 TMBA Basic Parameter
| Product Name | 3,4,5-Trimethoxybenzaldehyde |
| Synonyms | 3,4,5-methoxybenzaldehyde;3,4,5-TriMethoxybenzaldenyde;Three,four,five-preparationbenzaldehyde; 3,4,5-tiMethoxybenzaldehyde;3,4,5-TrimethoxybenZHldehyde;TrimetazidineImpurity9;OTAVA-BBBB7018801952 |
| CAS NO | 86-81-7 |
| Molecular Formula | C10H12O4 |
| Molecular Weight | 196.2 |
| EINECS | 201-701-6 |
| Melting Point | 72-74 °C (lit.) |
| Boiling Point | 163-165 °C/10 mmHg (lit.) |
| Flash Point | 163-165°C/10mm |
| Density | 1.2166 (rough estimate) |
| Storage | Keep in dark place, Sealed in dry, Room Temperature |
| Solubility | Soluble in methanol, solubility is 0.1g/mL, clear |
| Appearance | white to creamy powder or flakes |
TMBA Picture
What is 3,4,5-Trimethoxybenzaldehyde?
Uses
3,4,5-Trimethoxybenzaldehyde can be used as an intermediate in the synthesis of some pharmaceutical drugs including trimethoprim, cintriamide, roletamide, trimethoquinol (aka tretoquinol), and trimazosin as well as some psychedelic phenethylamines.
Preparation
Industrial scale
For industrial applications the chemical is synthesized from p-cresol using aromatic substitution with bromine followed by nucleophilic substitution with sodium methoxide. Oxidation of the methyl group to an aldehyde can occur via various synthetic methods.
Laboratory scale
At the laboratory scale the chemical is conveniently synthesized from vanillin or from Eudesmic acid’s Acyl chloride via Rosenmund reduction.
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